Item no.
TRC-I917590-10G
CAS Number
[108-12-3]
Unit
10 g
Shipment details
ADR Excepted Quantity (EQ) / AIR Excepted Quantity (EQ)
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Description
Application Notes: Isovaleryl Chloride is used as a reagent in the synthesis of NCT-501 and its analogs as potent and selective theophylline-based inhibitors of aldehyde dehydrogenase 1A1 (ALDH1A1). Isovaleryl Chloride is also used in the preparation of merestinib, a MET inhibitor.This compound is suitable for aldehyde dehydrogenase (ALDH) related research. /// References: Yang, S., et al.: J. Med. Chem., 58, 5967 (2015)| Frederick, M.O., et al.: Org. Process Res. Dev., 19, 1411 (2015)
Structure formula
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