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Description

Application Note: (2E)-N-[(1S,2S)-2-Hydroxy-1-methyl-2-phenylethyl]-N-methyl-2-pentenamide is an intermediate in the synthesis of (1R,2S)-Tapentadol Hydrochloride (T007230). (1R,2S)-Tapentadol is the (1R,2S)-isomer of Tapentadol (T007200, HCl), a novel, centrally acting oral analgesic with a dual mode of action that has demonstrated efficacy in preclinical and clinical models of pain relief.

Structure formula

(2E)-N-[(1S,2S)-2-Hydroxy-1-methyl-2-phenylethyl]-N-methyl-2-pentenamide

Contents

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TRC | Toronto Research Chemicals

Quality analytical standards and reference materials for food and environmental analysis, research

Founded in 1982, Toronto Research Chemicals is specialized in the development and production of reference materials used in research as well as food safety testing and environmental analysis. The range of more than 350,000 products includes reference standards for pesticides and metabolites, impurities, natural compounds and complex organic small molecules not otherwise commercially available.