Item no.
TRC-H941730-5MG
CAS Number
[636-00-0]
Unit
5 mg
Molecular formula
C8H12BrNO3
Molecular weight
250,09
Shipment details
No Dangerous Good /not restricted
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Description
Category: Amines, Aromatics, Neurochemicals, Pharmaceuticals, Intermediates and Fine Chemicals /// Appearance: Light Brown to Grey Solid /// Application Notes: 6-Hydroxydopamine is a selective catecholaminergic neurotoxin. Studies show that 6-Hydroxydopamine can be used to create an animal model of Parkinson's disease as it causes almost complete destruction of nigral dopaminergic neurons and their striatal terminals when injected into the substantia nigra of rats. 6-Hydroxydopamine induces apoptosis in PC12 cells. /// References: Soto-Otero, R. et al.: J. Neurochem., 74, 1605 (2000)| Fujita, H. et al.: Brain Res., 1113, 10 (2006)| Breese, G.R. et al.: 174, 313 (1970)|
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