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Description
Category: Inhibitors, Pharmaceuticals, Intermediates and Fine Chemicals /// Application Notes: E-64d is an inhibitor of cathepsins B and L as well as a potential inhibitor of calpain. E-64d has been shown to inhibit lysosomal proteases. E-64d has been used in combination with Prepstatin A to interfere with autolysosomal digestion. E-64d displays neurovascular and neuronal protective effects after focal cerebral ischemia in rats. /// References: Wilcox, D. et al.: Biochem. J., 285, 495 (1992)| McGowan, E.B. et al.: Biochem. Biophys. Res. Comm., 158, 432 (1989)| Tsubokawa, T. et al.: J. Neurosci. Res., 84, 832 (2006)|
Structure formula

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