Item no.
TRC-D471465-1G
CAS Number
[5856-77-9]
Unit
1 g
Shipment details
De Minimis
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Description
Appearance: Clear Colorless Oil /// Application Notes: 2,2-Dimethylbutanoyl chloride is a reagent that is used in the synthesis of 4alpha,5-Dihydro Simvastatin (D450010). 4alpha,5-Dihydro Simvastatin is an impurity in the synthesis of Simvastatin (S485000), a synthetic derivative of a fermentation product of Aspergillus terreus. A competitive inhibitor of HMG-CoA reductase. A synthetic analog of Lovastatin. Antilipemic. Simvastatin, the drug, is sold under the trade name Zocor. /// References: Hoffman, W.F., et al.: J. Med. Chem., 29, 849 (1986), Mol, M.J., et al.: Lancet, 2, 936 (1986)
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