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Description

Category: Pharmaceuticals, Intermediates and Fine Chemicals /// Application Notes: 7-O-Demethyl alpha-Narcotine, is a derivative of Narcotine (N378890), a noscapinoid class of microtubule binding compounds that alter microtubule dynamics without affecting tubulin polymer mass. Noscapinoids show great promise as chemotherapeutic agents for the treatment of human cancers. Unlike Narcotine, (-)-alpha-Narcotinediol deos not inhibit small-intestinal transport in rats. /// References: Naik, P. et al.: J. Mol. Mod., 18, 307 (2012)| Marazova, K. et al.: Pharmazie., 43, 561 (1988)

Structure formula

7-O-Demethyl alpha-Narcotine

Contents

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TRC | Toronto Research Chemicals

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Founded in 1982, Toronto Research Chemicals is specialized in the development and production of reference materials used in research as well as food safety testing and environmental analysis. The range of more than 350,000 products includes reference standards for pesticides and metabolites, impurities, natural compounds and complex organic small molecules not otherwise commercially available.