Item no.
TRC-C544002-10MG
Unit
10 mg
Molecular formula
C20H16D8FN5O3
Molecular weight
409,48
Shipment details
No Dangerous Good
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Description
Category: Drug Analogues, Isotope Labelled Compounds, Pharmaceuticals, Intermediates and Fine Chemicals /// Application Notes: CK 1827452-d8 is the labeled analogue of CK 1827452 (C544000), a promising new drug in systolic heart failure. It accelerates the transition of myosin into the force-generating state without affecting cardiac myocyte calcium homeostasis. CK 1827452 increases cardiac function by increasing the duration of ejection without changing the rates of contraction. /// References: Meijs, M. et al.: Eur. J. Heart. Fail., 14, 232 (2012)| Malik, F. et al.: J. Mol. Cell. Card., 51, 454 (2011)
Structure formula
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