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Description

Category: Aromatics, Heterocycles, Pharmaceuticals, Intermediates and Fine Chemicals /// Appearance: Off-White to Pale Yellow Solid /// Application Notes: 4-(3-Chlorophenyl)-4-oxo-2-butenoic Acid is an major metabolite of Tolvaptan (T536650), an selective, competitive arginine vasopressin V2 receptor antagonist used to treat hyponatremia (low blood sodium levels) associated with congestive heart failure, cirrhosis, and the syndrome of inappropriate antidiuretic hormone (SIADH). /// References: Wan, W. L., et al.: Chin. Chem. Lett., 23, 1343 (2012)| Dandia, A., et al.: J. Fluorine. Chem., 128, 524 (2007)|

Structure formula

4-(3-Chlorophenyl)-4-oxo-2-butenoic Acid

Contents

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Product data sheet

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Founded in 1982, Toronto Research Chemicals is specialized in the development and production of reference materials used in research as well as food safety testing and environmental analysis. The range of more than 350,000 products includes reference standards for pesticides and metabolites, impurities, natural compounds and complex organic small molecules not otherwise commercially available.