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Description
Category: Aromatics, Heterocycles, Pharmaceuticals, Intermediates and Fine Chemicals /// Appearance: Off-White to Pale Yellow Solid /// Application Notes: 4-(3-Chlorophenyl)-4-oxo-2-butenoic Acid is an major metabolite of Tolvaptan (T536650), an selective, competitive arginine vasopressin V2 receptor antagonist used to treat hyponatremia (low blood sodium levels) associated with congestive heart failure, cirrhosis, and the syndrome of inappropriate antidiuretic hormone (SIADH). /// References: Wan, W. L., et al.: Chin. Chem. Lett., 23, 1343 (2012)| Dandia, A., et al.: J. Fluorine. Chem., 128, 524 (2007)|
Structure formula
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