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Description

Appearance: Colourless Oil /// Application Notes: (17beta)-3,17-Bis(ethoxymethoxy)-estra-1,3,5(10)-triene is an intermediate in the synthesis of Estradiol 6-N3-Adenine which is a depurinating adduct that is created by the interaction of specific metabolites of estrogens in the body with DNA. Unfortunately, these adducts are endogeneous initiators of various human cancers, such as breast and prostate. /// References: Yang, L., et al.: Prostate, 69, 41 (2009)| Zahid, M., et al.: Chem. Res. Toxicol., 19, 164 (2006)| Zhang, Y., et al.: Metabol. Clin. Exp., 56, 887 (2007)

Structure formula

(17beta)-3,17-Bis(ethoxymethoxy)-estra-1,3,5(10)-triene

Contents

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TRC | Toronto Research Chemicals

Quality analytical standards and reference materials for food and environmental analysis, research

Founded in 1982, Toronto Research Chemicals is specialized in the development and production of reference materials used in research as well as food safety testing and environmental analysis. The range of more than 350,000 products includes reference standards for pesticides and metabolites, impurities, natural compounds and complex organic small molecules not otherwise commercially available.