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Description

Category: Aromatics, Heterocycles, Isotope Labelled Compounds, Pharmaceuticals, Intermediates and Fine Chemicals /// Appearance: Light Yellow Solid /// Application Notes: Azimilide-d8 Dihydrochloride is the isotope labelled analog of Azimilide dihydrochloride. Azimilide Dihydrochloride is an oral type III potassium channel blocker agent that blocks both the rapid activating component and the slow activating component of the delayed rectifier potassium current. Both preclinical and clinical studies have demonstrated the efficacy of azimilide and its safety in the treatment of supraventricular and ventricular tachyarrhythmia. Azimilide also is being studied in a worldwide multicenter trial for prevention of sudden cardiac death in patients after myocardial infarction. /// References: Tran, H.T., et al.: Heart. Dis., 1, 114 (1999)| Conway, E., et al.: Am. J. Cardiol., 102, 12 (2008)| Carlson, M., et al.: Exp. Rev. Cardio. Therap., 3, 387 (2005)| Dorian, P., et al.: J. Cardio. Pharm. Therap., 7, 211 (2002)|

Structure formula

Azimilide-d8 Dihydrochloride

Contents

Miscellaneous

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Product data sheet

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TRC | Toronto Research Chemicals

Quality analytical standards and reference materials for food and environmental analysis, research

Founded in 1982, Toronto Research Chemicals is specialized in the development and production of reference materials used in research as well as food safety testing and environmental analysis. The range of more than 350,000 products includes reference standards for pesticides and metabolites, impurities, natural compounds and complex organic small molecules not otherwise commercially available.