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Description
Category: Heterocycles, Protein Kinase Inhibitors and Activators /// Application Notes: AZD 7762 is studied as an cancer therapeutic agent due to its selective inhibitory activities towards checkpoint kinases, chk1 and chk2 by reversibly binding their respective ATP-binding sites within tumor cells. Recent research has also indicated AZD 7762 to possess enhancing effects towards other chk1 inhibitor lethality in glioblastoma cells. /// References: Sonya, D.Z., et al.: Mol Cancer Ther., 7, 2955 (2006)| Tang, D., et al.: Cancer. Bio. Ther., 13, 379 (2012)|
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