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TRC-A794750-100MG
Item no.
TRC-A794750-100MG
CAS Number
[34031-32-8]
Unit
100 mg
Shipment details
De Minimis

Description

Category: Carbohydrates and Derivatives, Pharmaceuticals, Intermediates and Fine Chemicals, Sulfur and Selenium Compounds /// Appearance: White to Off-White Solid /// Application Notes: Auranofin is a new oral gold-based antiarthritis drug. Auranofin inhibits various leukocyte activation pathways at multiple sites. Auranofin inhibits the release of inflammatory mediators from human macrophages, basophils, and pulmonary mast cells. Auranofin is an efficient inducer of mitochondrial membrane permeability transition pore in the presence of calcium ions related to its inhibition of mitochondrial thioredoxin reductase. /// References: Kizu, R., et al.: Chem. Pharm. Bull., 41, 1261 (1993), Itokazu, M., et al.: Clin. Ther., 17, 60 (1995), Kean, W.F., et al.: Br. J. Rheumatol., 36, 560 (1997)

Structure formula

Auranofin

Contents

Miscellaneous

Certificate of Analysis (specimen)

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Product data sheet

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TRC | Toronto Research Chemicals

Quality analytical standards and reference materials for food and environmental analysis, research

Founded in 1982, Toronto Research Chemicals is specialized in the development and production of reference materials used in research as well as food safety testing and environmental analysis. The range of more than 350,000 products includes reference standards for pesticides and metabolites, impurities, natural compounds and complex organic small molecules not otherwise commercially available.