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Description

Appearance: Light Brown Solid /// Application Notes: 1-[(3-Amino-4-quinolinyl)amino]-2-methyl-2-propanol is an intermediate in synthesizing Resiquimod-d5 (R144682), an isotope labelled Resiquimod (R144680) which is an imidazoquinoline derivative that acts as an immune response modifier. Resiquimod shows antitumor and antiviral activity and is used in the treatment of skin lesions such as herpes simplex virus. Resiquimod is a toll-like receptor 9 (TLR7) agonist. /// References: Wu, J.J. et al.: Antivir. Res., 64, 79 (2004)| Fife, K.H. et al.: Antimicrob. Agents Chemother., 52, 477 (2008)| Szeimies, R.M. et al.: Brit. J. Dermatol., 159, 205 (2008)

Structure formula

1-[(3-Amino-4-quinolinyl)amino]-2-methyl-2-propanol

Contents

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TRC | Toronto Research Chemicals

Quality analytical standards and reference materials for food and environmental analysis, research

Founded in 1982, Toronto Research Chemicals is specialized in the development and production of reference materials used in research as well as food safety testing and environmental analysis. The range of more than 350,000 products includes reference standards for pesticides and metabolites, impurities, natural compounds and complex organic small molecules not otherwise commercially available.