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Description

Category: Agonists, Amines, Aromatics, NeuroChemicals Pharmaceuticals, Intermediates and Fine Chemicals /// Application Notes: The enantiomer of (-)-alpha-Acetylmethadol (A186325), a synthetic opioid similar in structure to Methadone (M225865) used in the treatment of opiate dependence. (+)-alpha-Acetylmethadol is more effective than (-)-alpha-Acetylmethadol in competing for both 3H-ligands from the opiate receptors. /// References: Billings, R.E. et al.: Life Sci., 14, 1437 (1974)| Galici, R. et al.: Pharmacol. Biochem. Behav., 81, 626 (2005)| Xiao, Y. et al.: J. Pharmacol. Exp. Therap., 299, 366 (2001)| Horng, J.S. et al.: Res. Comm. Chem. Pathol. Pharmacol., 14, 621 (1976)|

Structure formula

(+)-alpha-Acetylmethadol Hydrochloride

Contents

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TRC | Toronto Research Chemicals

Quality analytical standards and reference materials for food and environmental analysis, research

Founded in 1982, Toronto Research Chemicals is specialized in the development and production of reference materials used in research as well as food safety testing and environmental analysis. The range of more than 350,000 products includes reference standards for pesticides and metabolites, impurities, natural compounds and complex organic small molecules not otherwise commercially available.