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Description

Skin is the largest organ in the body, with such diverse functions as mechanical barrier, thermoregulation, vitamin D synthesis, vitamin B folate protection, fluid homeostasis, sensation, and innate immunity. The skin responds to damage by up-regulating repair mechanisms and causing skin hyperproliferation. Consequently, analysis of biochemical components from the stratum corneum (SC) can be used to evaluate skin irritation, SC integrity and structure and inflammatory changes in human skin. The MILLIPLEX(R) Human Skin Panel is a 5-plex kit to be used for the simultaneous quantification of any or all of the following analytes in skin, skin tape extract or skin cell culture samples: cortisol, keratin-6, involucrin, keratin-1,10, and human serum albumin (HSA). The Luminex(R) xMAP(R) platform uses a magnetic bead immunoassay format for ideal speed and sensitivity to quantitate multiple analytes simultaneously, dramatically improving productivity while conserving valuable sample volume. Panel Type: Immune Response