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Description

Alkaline Phosphatase (AP) catalyzes the hydrolysis of the phosphate group in alkaline media. AP is an essential enzyme and widely distributes in a variety of tissues such as liver, intestine, kidney, bone, and placenta. Abnormal AP levels have been shown in numerous cancers, bone disease and liver dysfunction. AP is also expressed by pluripotent stem cells such as ES and IPS cells.The BioTracker CyP AP dye is a live cell near-infrared (NIR) fluorescent imaging probe for alkaline phosphatase. With its long emission wavelength, the probe is suitable for monitoring AP levels in both in vivo and in vitro tissues and cells. The probe possesses deep tissue penetration, less damage to the biological samples, and lower interference from the background fluorescence compared to other AP probes.Spectral PropertiesAbsorbance: 690nmEmission: 738nm