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Description

Gamma-glutamyltransferase, or GGT, is an enzyme that plays a key role in the gamma-glutamyl cycle, a pathway for the synthesis and degradation of glutathione and drug and xenobiotic detoxification. GGT is predominantly used as a diagnostic marker for liver disease and is often significantly increased in human malignancies and cancers.The BioTracker 525 Green GGT Dye is cancer-selective fluorescent imaging probe. This probe is rapidly activated by g-glutamyltranspeptidase (GGT), which is known to be tumor-associated enzyme, to give highly fluorescent compound. The membrane-permeable dye is applicable to live cell or in vivo imaging of cancer cells.Spectral PropertiesAbsorbance: 496nm Emission: 525nm