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Description

Maintenance of physiological balance in the body is attributed in part to normal kidney function. Altered kidney function due to injury, drug toxicity or kidney failure may be life threatening. Toxicity is the leading cause of drug failure, so research is expanding in search of more sensitive, rapid methods to determine organ-specific damage as quickly as possible. Traditionally, blood urea nitrogen (BUN) and serum creatinine tests have been used to determine drug-induced damage to the kidney. These tests only detect kidney damage after it begins and do not allow for the elucidation of where in the kidney the damage has occurred. Specificity and earlier detection of kidney injury is vital, and this area of research is expanding in search of more sensitive, rapid methods for determining the specific area of damage in kidney. The MILLIPLEX(R) portfolio provides valuable research assays to investigate multiple biomarkers of kidney injury in human serum and plasma samples using the [Luminex(R) xMAP(R) instrument platform.The MILLIPLEX(R) Human Kidney Injury Bead Panel 6 contains all the components necessary to measure the following four biomarkers in any combination using [Luminex(R) xMAP(R) technology: beta-2-Microglobulin (beta2M), Clusterin, Cystatin C, RBP4. The kit uses a 96-well format, contains a lyophilized standard cocktail, two quality controls and can measure up to 38 serum or plasma samples in duplicate. Panel Type: Toxicity