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Description

This Human Interleukin-6 (IL-6) Conferma(R) ELISA kit is used for the quantification of Human IL-6 in serum, plasma, or culture media samples. Human IL-6 is a soluble protein cytokine most commonly associated with the acute inflammatory response to infection or tissue damage.This is a 96 well format sandwich ELISA which uses our Conferma(R) process to ensure a high degree of lot to lot consistency. The process involves the physiochemical characterization of the ELISAs critical reagents lot to lot, with finished kits being evaluated using a sample library to bridge between lots. For detailed information on the process and a Verification report for this assay please click hereConferma(TM) Sandwich ELISAs Entrez Gene Summary:This gene encodes a cytokine that functions in inflammation and the maturation of B cells. In addition, the encoded protein has been shown to be an endogenous pyrogen capable of inducing fever in people with autoimmune diseases or infections.UniProt Summary:. ,Function: Cytokine with a wide variety of biological functions in immunity, tissue regeneration, and metabolism.. ,Size: 212 amino acids, 23,718 Da. ,Subunit: Component of a hexamer of two molecules each of IL6, IL6R and IL6ST.. ,Subcellular location: Extracellular region or secreted. ,Disease: Rheumatoid arthritis systemic juvenile (RASJ). A IL6 promoter polymorphism is associated with a lifetime risk of development of Kaposi sarcoma in HIV-infected men.. ,Similarity: Belongs to the IL-6 superfamily.