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Description

Corning Matrigel Growth Factor Reduced (GFR) Basement Membrane Matrix, 10 mL, is suited for applications requiring a highly defined basement membrane preparation. Available in standard GFR, High Concentration (HC), and Phenol Red-free formats. Corning Matrigel matrix is a solubilized basement membrane preparation extracted from the Engelbreth-Holm-Swarm (EHS) mouse sarcoma, a tumor rich in extracellular matrix proteins, including Laminin (a major component), Collagen IV, heparan sulfate proteoglycans, entactin/nidogen, and a number of growth factors.QualityMouse colonies routinely screened for pathogens via Mouse Antibody Production (MAP) testingExtensive PCR testing performed to screen for a number of pathogensTested and found negative for bacteria, fungi, and mycoplasmaProtein concentrations determined by Lowry methodEndotoxin units measured by Limulus Amoebocyte Lysate assayGel stability tested for a period of 14 days at 37CBiological activity determined for each lot using neurite outgrowth assay.SourceEHS mouse tumorApplicationCell Growth and DifferentiationMetabolism/Toxicology StudiesInvasion Assaysin vitro and in vivo Angiogenesis Assaysin vivo Angiogenesis Studies and Augmentation of Tumors in Immunosuppressed MicePreparation and StorageStore at -20C. Avoid multiple freeze-thaws.Click here for Corning Matrigel Lot Selection and Reservation.For Customers in California only: WARNING Please refer to Safety Data Sheet (SDS) Section 15 or Letter in Lieu for more information regarding California Proposition 65.