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Description

Protein A purified rabbit polyclonal antibody. Recognizes the ~67 kDa GTAP protein., The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes (E1s), ubiquitin-conjugating enzymes (E2s), and ubiquitin-protein ligases (E3s). GTAP is a member of the E2 ubiquitin-conjugating enzyme family. GTAP may participate in intercellular adhesion and embryonic development. GTAP is thought to play a role in stem cell development via its regulation of laminin-dependent embryonic cell adhesion and the formation of embryoid bodies., Anti-GTAP, rabbit polyclonal, recognizes the ~67 kDa GTAP protein in HEK293 cells. It is validated for use in Western blotting., Recognizes the ~67 kDa GTAP protein in HEK293 cells.Hu Entrez ID: 55585. ,Mu Entrez ID: 70093. ,Rat Entrez ID: 295292. ,Target NCBI Accession: HP 060052.3. ,Target SwissProt: Q7Z7E8