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Description

Quasi-orthogonally-protected Lys derivative. The Fmoc group can be removed selectively by treatment with piperidine, the Dde group is cleaved with 2% hydrazine in DMF [1]. When removing Dde in the presence of allyl-based protecting groups, allyl alcohol should be included in the deprotection solution to prevent reduction of the allyl group [2].Also available Fmoc-Lys(Dde)-OH 852057.This derivative has been employed in Fmoc SPPS to facilitate the introduction of biotin to the side-chain of lysine [3].The product number for this product was previously 04-12-5201.To obtain a certificate of analysis (CoA) of a lot that begins with the letter &ldquo,A&rdquo,, please select the option in the right hand menu &ldquo,Request a COA for Lot#s starting with A&rdquo,.