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Wnt Agonist I in DMSO - CAS 853220-52-7 - Calbiochem The Wnt Agonist I in DMSO, also referenced under CAS 853220-52-7, controls the biological activity of Wnt. This small molecule/inhibitor is primarily used for Cancer applications.

Item no.

SAF-681664-2MG

CAS Number

[853220-52-7]

Unit

1 x 2 mg

Molecular formula

C19H18N4O3

Molecular weight

350,37

Shipment details

No Dangerous Good

Price on request

Description

A cell-permeable, potent, and selective activator of Wnt signaling that does not inhibit the activity of GSK-3beta (IC50 >60 µ,M). Shown to mimic the effect of Wnt and induce beta-catenin and TCF (T-cell fate)-dependent transcriptional activity (EC50 = 700 nM in HEK-293T cells). Reported to cause substantial head defects during Xenopus embryonic development. The solid form of this compound (Cat. No. 681665) is also available.

Structure formula

Miscellaneous

Certificate of Analysis (specimen)

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Product data sheet

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