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Tubulin Polymerization Inhibitor II The Tubulin Polymerization Inhibitor II, also referenced under CAS 1151995-69-5, acts as an effective anti-microtubule agent. This small molecule/inhibitor is primarily used for Cell Structure applications.

Item no.

SAF-654164-5MG

CAS Number

[1151995-69-5]

Unit

1 x 5 mg

Molecular formula

C19H19NO5

Molecular weight

341,36

Shipment details

No Dangerous Good

Price on request

Description

A cell-permeable, SU5416- (Cat. Nos. 676487 and 676498) derived combretastatin A-4 (Cat. No. 234200) analog that acts as an effective anti-microtubule agent (IC50 = 4.5 µ,M in inhibiting polymerization of purified porcine brain tubulin) and displays extremely potent anti-proliferative activity towards various cancer cell lines (GI50<10 nM for 46 lines among a 53 NCI panel tested).

Structure formula

Miscellaneous

Certificate of Analysis (specimen)

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Product data sheet

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