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TGF-beta RI Kinase Inhibitor III - CAS 356559-13-2 - Calbiochem The TGF-beta RI Kinase Inhibitor III, also referenced under CAS 356559-13-2, controls the biological activity of TGF-beta RI Kinase. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.

Item no.

SAF-616453-2MG

CAS Number

[356559-13-2]

Unit

1 x 2 mg

Molecular formula

C20H22ClN3O2

Molecular weight

335,40 (anhydrous free base basis)

Shipment details

No Dangerous Good /not restricted

Price on request

Description

A cell-permeable imidazolyl-pyridine compound that acts as a potent, ATP-competitive, reversible, and selective inhibitor of activin receptor-like kinase 4 (IC50 = 129 nM), 5 ( IC50 = 47 nM), and 7. It inhibits p38 MAPKalpha only at much higher concentrations (IC50 = 10.6 µ,M) and has little effect against ALK1/2/3/6 as well as a panel of 26 other kinases.

Hazards

Structure formula

Miscellaneous

Certificate of Analysis (specimen)

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Product data sheet

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