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Description

A potent inhibitor of human telomerase (IC50 = 6.5 µ,M). TMPyP4 binds strongly to DNA quadruplexes by stacking on the G-tetrads at the core of the quadruplex, resulting in telomerase inhibition. Fluoresces intensely in the presence of quadruplex DNA., A potent inhibitor of human telomerase (IC50 = 6.5 µ,M). TMPyP4 binds strongly to DNA quadruplexes by stacking on the G-tetrads at the core of the quadruplex, resulting in telomerase inhibition. Fluoresces highly in the presence of quadruplex DNA.

Hazards

Harmful

Structure formula

5,10,15,20-Tetrakis(1-methyl-4-pyridinio)porphyrin tetra(p-toluenesulfonate)

Contents

Miscellaneous

Certificate of Analysis (specimen)

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Product data sheet

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