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Telomerase Inhibitor IX - CAS 368449-04-1 - Calbiochem The Telomerase Inhibitor IX, also referenced under CAS 368449-04-1, controls the biological activity of Telomerase. This small molecule/inhibitor is primarily used for Cell Structure applications.

Item no.

SAF-581011-10MG

CAS Number

[368449-04-1]

Unit

1 x 10 mg

Price on request

Description

A cell-permeable, bis-catechol containing, m-phenylenediamide compound that displays anti-proliferative properties. Acts as a potent, reversible inhibitor of telomerase activity (IC50 = 670 nM, TRAP lysate prepared from U937 cells). Prolonged treatment with MST-312 has been reported to result in telomere shortening and growth arrest in U937 cells. Does not inhibit the activity of Taq DNA polymerase (IC50 >3 µ,M).

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Structure formula

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