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Description

Recombinant, human alpha-synuclein containing an A53T mutation and expressed in E. coli. A point mutant (A53T) of alpha-synuclein gene that has been linked to autosomal dominant early-onset Parkinson's disease (PD)., Recombinant, human alpha-synuclein containing an A53T mutation and expressed in E. coli. alpha-synuclein is an acidic neuronal protein of 140 amino acids that has been implicated in the pathogenesis of Parkinson's disease and related neurodegenerative disorders. alpha-Synuclein (A53T) is a point mutant of the alpha-synuclein gene that has been linked to autosomal dominant early onset Parkinson's Disease (PD). The apparent molecular weight on SDS-PAGE is ~19-20 kDa.