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Syk Inhibitor IV, BAY 61-3606 - CAS 732938-37-8 - Calbiochem The Syk Inhibitor IV, BAY 61-3606, also referenced under CAS 732938-37-8, controls the biological activity of Syk. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.

Item no.

SAF-574714-2MG

CAS Number

[732983-37-8]

Unit

1 x 2 mg

Molecular formula

C20H18N6O3

Molecular weight

390,40 (anhydrous free base basis)

Shipment details

No Dangerous Good /not restricted

Price on request

Description

A cell-permeable imidazopyrimidine compound that acts a potent, ATP-competitive, reversible, and highly selective inhibitor of Syk tyrosine kinase activity (IC50 = 10 nM) with no inhibitory effect against Btk, Fyn, Itk, Lyn, and Src even at concentrations as high as 4.7 µ,M. Shown to inhibit Syk-mediated cellular functions in vitro and exhibit good oral bioavailability and in vivo effacacy in the treatment of various allgery and asthma conditions in rat models.

Structure formula

Miscellaneous

Certificate of Analysis (specimen)

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Product data sheet

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