Item no.
SAF-574713-50MG
CAS Number
[1485-00-3]
Unit
1 x 50 mg
Molecular formula
C9H7NO4
Molecular weight
193,16
Shipment details
No Dangerous Good
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Description
A cell-permeable nitrostyrene compound that acts as a selective inhibitor of Syk kinase activity (IC50 = 2.5 µ,M). It inhibits Src only at much higher concentrations (IC50 = 29.3 µ,M) and exhibits little effect against Fak and JAK2. Shown to potently inhibit platelet aggregation induced by various stimulators, including U46619, ADP, arachidonic acid, collagen, thrombin, ionophore A23187, and PDBu (IC50 ranges from 2.1 to 25.9 µ,M).
Structure formula
Contents
Miscellaneous
Certificate of Analysis (specimen)
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Product data sheet
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