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SIRT1 Activator II - CAS 374922-43-7 - Calbiochem The SIRT1 Activator II, also referenced under CAS 374922-43-7, modulates the biological activity of SIRT1. This small molecule/inhibitor is primarily used for Biochemicals applications.

Item no.

SAF-566313-10MG

Unit

1 x 10 mg

Shipment details

No Dangerous Good

Price on request

Description

A cell-permeable pyrroloquinoxaline compound that acts as a reversible SIRT1 activator (10 µ,M causes ~2.3-fold fluorescent enhancement in a fluorescent assay using hrSIRT1) and enhances fat mobilization in fully differentiated 3T3L1 fibroblasts. Shown to inhibit LPS-induced TNF-alpha release in THP-1 cells by ~10-fold more potent than resveratrol (Cat. No. 554325).

Structure formula

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