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beta-Secretase Inhibitor II - CAS 263563-09-3 - Calbiochem The beta-Secretase Inhibitor II, also referenced under CAS 263563-09-3, controls the biological activity of beta-Secretase. This small molecule/inhibitor is primarily used for Neuroscience applications.

Item no.

SAF-565749-5MG

Unit

1 x 5 mg

Price on request

Description

A potent, cell-permeable, and reversible inhibitor of beta-secretase that corresponds to the beta-secretase cleavage site (VNL-DA) of the Swedish mutant Amyloid Precursor Protein (APP). Inhibits the formation of both Abetatotal (IC50 = 700 nM) and Abeta1-42 (IC50 = 2.5 µ,M) in Chinese hamster ovary (CHO) cells stably transfected with wild-type APP751., A potent, cell-permeable, and reversible inhibitor of beta-secretase. Corresponds to the beta-secretase cleavage site (VNL-DA) of the Swedish mutant Amyloid Precursor Protein (APP). Inhibits the formation of both Abetatotal (IC50 = 700 nM) and Abeta1-42 (IC50 = 2.5 µ,M) in Chinese hamster ovary (CHO) cells stable transfected with wild-type APP751.

Structure formula

Z-VLL-CHO, N-Benzyloxycarbonyl-Val-Leu-leucinal

Miscellaneous

Certificate of Analysis (specimen)

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Product data sheet

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