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RNA Polymerase III Inhibitor - CAS 577784-91-9 - Calbiochem RNA Polymerase III Inhibitor, CAS 577784-91-9, is a cell-permeable inhibitor of RNA Polymerase III (IC?? = 27 and 32 µM for human and S. cerevisiae RNA Pol III, respectively).

Item no.

SAF-557403-10MG

Unit

1 x 10 mg

Price on request

Description

A cell-permeable inhibitor of RNA polymerase III (RNA Pol III) (IC50 = 27 µ,M for human RNA Pol III and 32 µ,M for Saccharomyces cerevisiae RNA Pol III). Inhibits cell growth in yeast by preventing RNA Pol III-mediated tRNA transcription., A cell-permeable indazolo-sulfonamide compound that displays broad-spectrum inhibitory activity against RNA Polymerase III (IC50 = 27 and 32 µ,M for human and S. cerevisiae RNA Pol III, respectively). Inhibits cell growth in yeast by preventing RNA Pol III-mediated tRNA transcription. Also available as a 25 mM solution in DMSO (Cat. No. 557404).

Structure formula

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