Item no.
SAF-551476-5MG
Unit
1 x 5 mg
Shipment details
No Dangerous Good
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Description
A cell-permeable, irreversible, broad-spectrum caspase inhibitor (IC50 = 50, 100, 430, and <25 nM for caspase-1,-8, -9, and -3, respectively) with effective antiapoptotic properties against all major caspase-mediated cellular apoptosis pathways. Exhibits no cytotoxic effects even at extremely high concentrations. Shown to reduce ischemic brain damage and stroke-induced programmed cell death in thymus and spleen.
Structure formula
Miscellaneous
Certificate of Analysis (specimen)
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Product data sheet
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