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InSolution PTP1B Inhibitor - Calbiochem The InSolution PTP1B Inhibitor controls the biological activity of PTP1B. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.

Item no.

SAF-539749-2MG

Unit

1 x 2 mg

Shipment details

No Dangerous Good

Price on request

Description

A cell-permeable, selective, reversible, and non-competitive allosteric inhibitor of PTP1B (IC50 = 4 µ,M and 8 µ,M for PTP1B403 and PTP1B298, respectively). Binds to a novel site away from the catalytic pocket and inhibits PTP1B activity by preventing closure of the WPD loop.

Structure formula

Miscellaneous

Certificate of Analysis (specimen)

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Product data sheet

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