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Protein Arginine N-Methyltransferase Inhibitor, AMI-1 - Calbiochem The Protein Arginine N-Methyltransferase Inhibitor, AMI-1 controls the biological activity of Protein Arginine N-Methyltransferase. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.

Item no.

SAF-539209-5MG

Unit

1 x 5 mg

Molecular formula

C21H12N2Na4O9S2

Molecular weight

592,42

Price on request

Description

A cell-permeable, symmetrical sulfonated urea compound that acts as a potent, specific and non-AdoMet (S-adenosyl-L-methionine, SAM)-competitive inhibitor of protein arginine N-methyltransferases (PRMTs, IC50 = 8.81 µ,M for PRMT1 and 3.03 for yeast-RMT1p) with minimal effect on lysine methyltransferases. Inhibits nuclear receptor reporter gene activation in MCF-7 cells, and HIV-1 RT polymerase (IC50 = 5 µ,M).

Structure formula

Miscellaneous

Certificate of Analysis (specimen)

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Product data sheet

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