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Proteasome Inhibitor II - Calbiochem The Proteasome Inhibitor II controls the biological activity of Proteasome. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.

Item no.

SAF-539162-5MG

Unit

1 x 5 mg

Molecular formula

C29H39N3O5

Molecular weight

509,64

Price on request

Description

A potent, cell-permeable, and reversible proteasome inhibitor. Inhibits the chymotrypsin-like activity of the pituitary multicatalytic proteinase complex (MPC, Ki = 460 nM). Does not inhibit the peptidyl-glutamyl peptide hydrolyzing activity of MPC even at concentrations of 200 µ,M. Also blocks the decay of IkappaB-alpha and IkappaB-beta proteins in exponentially growing WEHI 231 cells.

Structure formula

Miscellaneous

Certificate of Analysis (specimen)

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Product data sheet

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