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Description

An imidazolo-oxindole compound that acts as a potent, ATP-binding site directed inhibitor of PKR. Shown to effectively inhibit RNA-induced PKR autophosphorylation (IC50 = 210 nM) and rescue PKR-dependent translation block (IC50 = 100 nM). The solid form of this compound (Cat. No. 527450) is also available.

Structure formula

Imidazolo-oxindole PKR inhibitor C16

Contents

Miscellaneous

Certificate of Analysis (specimen)

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Product data sheet

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