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Description
A sesquiterpene lactone with anti-inflammatory, antisecretory, and spasmolytic properties. Inhibits the expression of COX-2 and proinflammatory cytokines (TNF-alpha and IL-1) in LPS-stimulated macrophages. Also inhibits NF-kappaB and activation of MAP kinase., A cell-permeable sesquiterpene lactone with anti-inflammatory, antisecretory, and spasmolytic properties. Inhibits the expression of COX-2 and proinflammatory cytokines (TNF-alpha and IL-1) in LPS-stimulated macrophages. Also inhibits NF-kappaB and activation of MAP kinase.
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