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Description

A cell-permeable myristoylated hexapeptide derived from EXE-motif-containing integrin beta3 subunit that selectively inhibits integrin outside-in signaling without affecting inside-out signaling . Shown to specifically block the interaction of Galpha3 and integrin beta3 subunit resulting in the inhibition of Galpha13-dependent early phase outside-in signaling. Selectively inhibits thrombosis without affecting haemostasis., A cell-permeable myristoylated hexapeptide derived from EXE-motif-containing integrin beta3 subunit that selectively inhibits integrin outside-in signaling without affecting inside-out signaling . Shown to specifically block the interaction of Galpha3 and integrin beta3 subunit resulting in the inhibition of Galpha13-dependent early phase outside-in signaling. Selectively inhibits thrombosis without affecting haemostasis.Please note that the molecular weight for this compound is batch-specific due to variable water content.