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Neurogenesis Inducer V, KHS101 - Calbiochem A blood brain barrier permeable pyrimidinyl-aminothiazole compound that specifically interacts with TACC3 (transforming acidic coiledcoil-containing protein 3) and promotes nuclear localization of ARNT2 (aryl-hydrocarbon receptor nuclear translocator 2).

Item no.

SAF-480747-10MG

Unit

1 x 10 mg

Molecular formula

C18H21N5S

Molecular weight

339,46

Shipment details

No Dangerous Good

Price on request

Description

A blood brain barrier permeable pyrimidinyl-aminothiazole compound that specifically interacts with TACC3 (transforming acidic coiledcoil-containing protein 3) and promotes nuclear localization of ARNT2 (aryl-hydrocarbon receptor nuclear translocator 2). Shown to significantly induce neuronal differentiation of cultured rat hippocampal NPCs (neural progenitor cells, EC50 ~ 1 µ,M) and in adult rats (6 mg/kg, s.c.) and suppress proliferation.

Structure formula

N?-Isobutyl-N²-((2-phenylthiazol-4-yl)methyl)pyrimidine-2,4-diamine

Analyte	CAS Number	Concentration	Unit	Additional information	Method
N?-Isobutyl-N²-((2-phenylthiazol-4-yl)methyl)pyrimidine-2,4-diamine

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