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Monastrol - CAS 254753-54-3 - Calbiochem A potent, cell-permeable, non-tubulin-interacting mitosis inhibitor.

Item no.

SAF-475879-5MG

Unit

1 x 5 mg

Description

A potent, cell-permeable, non-tubulin-interacting mitosis inhibitor. Arrests mammalian cells in mitosis with monopolar spindles. In vitro, it specifically inhibits the motility of the mitotic kinesin Eg5, a motor protein involved in the assembly and maintenance of the mitotic spindle (IC50 = 14 µ,M)., A potent, cell-permeable, nontubulin-interacting mitosis inhibitor. Arrests mammalian cells in mitosis with monopolar spindles. In vitro, it specifically inhibits the motility of the mitotic kinesin Eg5, a motor protein involved in the assembly and maintenance of the mitotic spindle (IC50 = 14 µ,M).

Structure formula

4-(3-Hydroxyphenyl)-6-methyl-2-thioxo-1,2,3,4-tetrahydro-4H-pyrimidin-5-carboxylic Acid Ethyl Ester

Analyte	CAS Number	Concentration	Unit	Additional information	Method
4-(3-Hydroxyphenyl)-6-methyl-2-thioxo-1,2,3,4-tetrahydro-4H-pyrimidin-5-carboxylic Acid Ethyl Ester	[254753-54-3]

Miscellaneous

Certificate of Analysis (specimen)

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Product data sheet

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