Item no.
SAF-474791-1MG
Unit
1 x 1 mg
Shipment details
No Dangerous Good
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Description
Potent, reversible, and cell-permeable proteasome inhibitor (Ki = 4 nM). Reduces the degradation of ubiquitin-conjugated proteins in mammalian cells and permeable stains of yeast by the 26S complex without affecting its ATPase or isopeptidase activities. Activates c-Jun N-terminal kinase (JNK1) and inhibits NF-kappaB activation (IC50 = 3 µ,M).
Structure formula
Contents
Miscellaneous
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