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MMP-2/MMP-3 Inhibitor III, PD166793 - CAS 199850-67-4 - Calbiochem The MMP-2/MMP-3 Inhibitor III, PD166793, also referenced under CAS 199850-67-4, controls the biological activity of MMP-2/MMP-3. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.

Item no.

SAF-444284-5MG

Unit

1 x 5 mg

Shipment details

No Dangerous Good

Price on request

Description

A cell-permeable biphenylsulfonylvaline compound that acts as a potent inhibitor against MMP-2, -3, and -13 (IC50 = 47, 12, and 8 nM, respectively) and a weaker inhibitor against AMP deaminase (20% inhibition at 0.1 µ,M), MMP-1, -7, -9, and -14 (IC50 = 6.1, 7.2, 7.9, and 0.24 µ,M, respectively). Shown to offer therapeutic benefits in vivo in various animal models of heart failure and diabetes.

Structure formula

Miscellaneous

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Product data sheet

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