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Description

"A multifunctional, secreted glycoprotein that acts as a broad range irreversible protease inhibitor that forms a ""trap"" around most proteases. alpha2M is so large a molecule that it tends to remain intravascular. Localized on the surface of peripheral blood lymphocytes. Multifunctional activities include promoting growth of mammalian cells in culture, stimulating regeneration of lymphocytes in irradiated mice, transporting zinc, and acting as proteinase inhibitor that controls the clotting and fibrinolytic system."