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Caspase-1 Inhibitor II - CAS 178603-78-6 - Calbiochem The Caspase-1 Inhibitor II, also referenced under CAS 178603-78-6, controls the biological activity of Caspase-1. This small molecule/inhibitor is primarily used for Cancer applications.

Item no.

SAF-400012-5MG

Unit

1 x 5 mg

Shipment details

No Dangerous Good

Price on request

Description

Interleukin-1beta converting enzyme (ICE) is a cysteine protease that cleaves the IL-1beta precursor to mature IL-1beta. Caspase-1 inhibitor II is a cell-permeable, irreversible inhibitor of Caspase-1, Caspase-4, and Caspase-5. Inhibits CPP32/Apopain at a much higher concentration. Inhibits Fas-mediated apoptosis and acidic sphingomyelinase activation., A cell-permeable and irreversible inhibitor of caspase-1 (Ki = 760 pM), caspase-4, and caspase-5. Inhibits Fas-mediated apoptosis and acidic sphingomyelinase activation.

Structure formula

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