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Histone Deacetylase Inhibitor VI, HNHA - CAS 926908-04-5 - Calbiochem The Histone Deacetylase Inhibitor VI, HNHA, also referenced under CAS 926908-04-5, controls the biological activity of Histone Deacetylase.

Item no.

SAF-382172-10MG

Unit

1 x 10 mg

Shipment details

No Dangerous Good

Price on request

Description

A cell-permeable hydroxyamide-based SAHA analog that potently inhibits histone deacetylase (HDAC) activity (IC50 = 100 nM). Shown to induce histone acetylation and p21 transcription with concomitent inhibition of cell cycle progression in human fibrosarcoma HT1080 cells. Reported to be more potent than SAHA in inhibiting tumor growth in a murine xenograph model in vivo.

Structure formula

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