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Description

A cell-permeable furan carboxamide compound that acts as a potent, reversible, and ATP-competitive cFMS/CSF-1R inhibitor that blocks cFMS autophosphorylation both in CSF-1/M-CSF-stimulated HEK-293 cells (IC50 = 76 nM) and in cell-free in vitro kinase assays (IC50 = 17 nM).

Structure formula

5-Cyano-N-(2,5-di(piperidin-1-yl)phenyl)furan-2-carboxamide

Contents

Miscellaneous

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