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ErbB2 Inhibitor II - CAS 928207-02-7 - Calbiochem The ErbB2 Inhibitor II, also referenced under CAS 928207-02-7, controls the biological activity of ErbB2. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.

Item no.

SAF-324732-5MG

Unit

1 x 5 mg

Shipment details

No Dangerous Good

Price on request

Description

A cell-permeable triazole compound that targets the ATP-binding site of erbB2/HER2 and reduces the phosphorylation of erbB2 in MDA-MB-453 cells (IC50 = 6.6 µ,M), but not that of the overexpressed erbB1 in MDA-MB-468 cells even at concentrations as high as 100 µ,M. Shown to suppress MDA-MB-453 growth with an IC50 of 30.9 µ,M.

Structure formula

4-(3-Phenoxyphenyl)-5-cyano-2H-1,2,3-triazole

Miscellaneous

Certificate of Analysis (specimen)

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Product data sheet

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